Mabthera Or Ristova
Brand Name - Ristova
Generic - Rituximab
Strength - 500 Mg and 100mg
Packing - 1 vial of 50 ml of concentrate for solution for infusion
Manufactured by - Roche
MabThera is used in adults to treat non-Hodgkin’s lymphoma. chronic lymphocytic leukaemia and rheumatoid arthritis (a disease that causes inflammation of the joints).
In non-Hodgkin’s lymphoma, MabThera is used to treat two types of the disease, both of which affect B-lymphocytes:
In follicular lymphoma, MabThera is used in combination with chemotherapy . It can also be used as maintenance treatment in patients whose follicular lymphoma has responded to initial chemotherapy.
In patients with diffuse large B-cell lymphoma, MabThera is used in combination with chemotherapy ‘CHOP’ (cyclophosphamide, doxorubicin, vincristine and prednisolone).
Mechanism of action:
The antibody binds to CD20. CD20 is widely expressed on B cells, from early pre-B cells to later in differentiation, but it is absent on terminally differentiated plasma cells. CD20 does not shed, modulate or internalise. Although the function of CD20 is unknown, it may play a role in Ca2+ influx across plasma membranes, maintaining intracellular Ca2+ concentration and allowing activation of B cells.
Headache, fever, chills, nausea, heartburn, flushing, weakness, or dizziness may occur.
Ristova ( Rituximab )should be stored at 2 C - 8 C (36 F - 36 F) and protected from sunlight.
Rituximab injection should be taken on doctor prescription only.
K M Healthcare is supplier of Mabthera. K M Healthcare is supplier of Generic Rituximab injections from India. Generic Rituximab is avaolable with the brand name of Reditux by Dr. Reddy, Mabtas by Intas. And From Hetero Also.
K M Healthcare supply Rituximab injection world wide.
- Item Code: MabThera